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Wednesday, May 16, 2012, 7:30 pm Room M-114, Stanford University Medical School Optional dinner location: Stanford Hospital Cafeteria, 6:15 PM (no host, no reservations) Integrated Food and Activity Sensors Provide Behavioral Feedback for Successful Weight Loss with abiliti® Gastric Stimulation System in Obese Subjects Rose Province Principal Scientist, Intrapace, Inc Abstract: Obesity is a chronic disease which has become pandemic. The prevalence of worldwide obesity has more than doubled since 1980. In 2008, 1.5 billion adults were overweight. Of these 500 million were obese. While non-surgical management of obesity is favorable, numerous studies have shown that it is ineffective in producing and maintaining clinically significant weight loss. Surgical approaches are thus considered the only viable options for long term success in weight loss. There is a need for alternatives that are less invasive and devoid of severe complications. Gastric electrical stimulation (GES) has been recently introduced as an obesity treatment, and while clinical outcomes have been mixed, significant reductions in food intake and weight loss have been demonstrated. This talk will present the abiliti® system which was developed by Intrapace, Inc to treat obesity with GES, and in addition promotes behavioral change by providing consumption and physical activity data to patient and physicians. The intragastric and activity sensor technology will be discussed, as well as the clinical evaluation. Biography: Rose Province received an MS in Biomedical Engineering from Johns Hopkins University in 1991. She has worked in the medical device industry for 20 years including the areas of cardiac rhythm management with St. Jude Medical, sleep apnea therapy with Inspiration, Inc., and at IntraPace, Inc in the area of obesity treatment. At IntraPace, her main involvement has been development of algorithms to provide exercise diagnostics from the implanted 3D accelerometer, and basic research to develop improved means for detecting food intake and enhance the efficacy of the gastric stimulation. She does clinical and basic research to further develop medical device therapy, and is a named inventor in 10 patents related to defibrillation technology, and 3 patents in the area of breathing control with electrical stimulation. Watch this space and the IEEE Grid Calendar for upcoming meeting announcements. 
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