Ferramenta que integra programas baseados no método de distancia para reconstrução de arvores filogenéticas (Tool that integrates distance based programs for reconstructing phylogenetic trees)

Martha Torres (mxtd2000@yahoo.com.br)1, G Dias (grodias@gmail.com)1, G Gonçalves (gdgnw@yahoo.com.br)2, C Vieira (cristiannomartins@gmail.com)3


1Universidade Estadual de Santa Cruz
2Universidade Federal de Minas Gerais
3Universidade Estadual de Campinas

This paper appears in: Revista IEEE América Latina

Publication Date: Sept. 2011
Volume: 9,   Issue: 5 
ISSN: 1548-0992


Abstract:
The main existing methods for reconstructing phylogenetic trees are based on maximum likelihood, bayesian inference, maximum parsimony or distance. There are many distance based programs for phylogenetic trees reconstruction. The five most important distance based programs were selected: NJ, BioNJ, UPGMA, Weighbor and FastME. Synthetic data sets were applied in order to evaluate the distance-based methods under consideration. Then, the tool DiGrafu was developed, so as to exploit the best characteristics of these programs. Besides, the validation of this proposed solution was presented using real data.

Index Terms:
bioinformatics, phylogenetic tree reconstruction, distance methods   


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