Citotoxicidad de Hidroxiapatita y su morfología en composites con Ti (Cytotoxicity of hydroxyapatite and morphology in composites with Ti)

Romina Comín (romicomin@gmail.com), Laura A. Reyna (lreyna@efn.uncor.edu), Mariana P. Cid (manacid@hotmail.com), Carlos R. Oldani (), Nancy A. Salvatierra (nsalvatierra@com.uncor.edu)


Universidad Nacional de Córdoba
This paper appears in: Revista IEEE América Latina

Publication Date: Feb. 2013
Volume: 11,   Issue: 1 
ISSN: 1548-0992


Abstract:
Hydroxyapatite (Ca10(PO4)6(OH)2 is the material used to improve osseointegration of implants in humans. Traditionally Ti-based implant is coated with hydroxyapatite, but this presents several problems such as, low fracture toughness of hydroxyapatite, generation of interfacial cracks during the deposition step and low adhesion ceramic /metal. Furthermore some studies reported that some excellent Ti‑HA bio-composites could be fabricated by the powder metallurgy (PM) technology. In present study it was investigate the cytotoxicity of coralline and bovine hydroxyapatite. Topography of Ti-HA composites obtained by powder metallurgy was evaluated by scanning electron microscopy. The results showed that HA samples analyzed did not affect cell viability. Furthermore, a good integration of HA to the matrix of Ti was observed by microscopy studies

Index Terms:
Hydroxyapatite, Ti-HA composites, biocompatibility, powder metallurgy   


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