Estudio de Diseño para la Integración de un Bioreactor de Cultivo Celular con un Sistema de Estimulación Magnética (Design Study for a Cellular Culture Bioreactor Coupled with a Magnetic Stimulation System)

Andres F. Restrepo (andres.restrepo@correounivalle.edu.co), Luis J. Martínez (luis.j.martinez.g@gmail.com), Carlos R. Pinedo (carlos.pinedo@correounivalle.edu.co), Edinson Franco (edinson.franco@correounivalle.edu.co), Héctor Cadavid (hector.cadavid@correounivalle.edu.co)


Universidad del Valle
This paper appears in: Revista IEEE América Latina

Publication Date: Feb. 2013
Volume: 11,   Issue: 1 
ISSN: 1548-0992


Abstract:
This article presents a design study performed to integrate a cellular culture bioreactor along with an external magnetic stimulation system, aimed at creating ideal environmental conditions that allow for cellular culture and cellular tissue growth to take place in three dimensions, under a sterile environment favorable for the development of bioorganic grafts which have been exposed to controlled electromagnetic fields. The different systems that have been designed and constructed are described along with their particular characteristics and all general considerations that were taken into account during the design process are presented, as well as the main variables that must be considered during implementation in order to guarantee constant and adequate function of the integrated systems, as well as reproducible results.

Index Terms:
bioreactor, magnetic stimulation, cell cultures, cellular proliferation, integration   


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