Segmentación de Biopsias de Médula Ósea mediante Morfología Matemática Color (Segmentation of Bone Marrow Biopsies by Mathematical Morphology in Color Spaces)

Juan I. Pastore (jpastore@fi.mdp.edu.ar), Agustina Bouchet (abouchet@fi.mdp.edu.ar), Emilce Moler (emoler@fi.mdp.edu.ar), Virginia Ballarin (vballari@fi.mdp.edu.ar)



This paper appears in: Revista IEEE América Latina

Publication Date: Feb. 2013
Volume: 11,   Issue: 1 
ISSN: 1548-0992


Abstract:
Anatomic and pathologic reports of histological slides give results indicating the presence of trabeculae, hematopoietic and fat cells. This allows evaluating the grade of some metabolic disorder, comparing normal values with pathological ones. Generally, quantifications are carried out by simple visual inspection presenting big inter-and intra-user differences. This work presents an automatic method for detecting different types of tissues in bone marrow biopsies using Mathematical Morphology in color spaces, in order to determine the marrow cellularity accurately. The method was tested with 30 images of bone marrow biopsies presenting different distributions of cellularity.

Index Terms:
Bone Marrow Biopsies, Segmentation, Mathematical Morphology, Color Spaces   


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